Effective integration of information technologies into the higher education system is aimed at improving the quality of education, developing students ' creative abilities, and striving for continuous acquisition of new knowledge. The work of students with situational tasks contributes to the formation of analytical thinking, stimulates the deepening and expansion of knowledge not only in a certain subject area, but also in the corresponding related areas. The article describes the experience of using situational tasks to control theoretical and practice-oriented knowledge of students on a number of topics in the section "Statistical analysis of biomedical research" as part of the discipline Medical informatics. The prospects of implementing situational tasks in an interactive form using the capabilities of modern information and communication technologies are substantiated.